No treatment options are currently available to counteract cognitive deficits and/or delay progression towards dementia in older people with mild cognitive impairment (MCI). The ‘Train the Brain’ programme is a combined motor and cognitive intervention previously shown to markedly improve cognitive functions in MCI individuals compared to non-trained MCI controls, as assessed at the end of the 7-month intervention. Here, we extended the previous analyses to include the long-term effects of the intervention and performed a data disaggregation by gender, education and age of the enrolled participants. We report that the beneficial impact on cognitive functions was preserved at the 14-month follow-up, with greater effects in low-educated compared to high-educated individuals, and in women than in men. © The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved.
Long-term beneficial impact of the randomised trial ‘Train the Brain’, a motor/cognitive intervention in mild cognitive impairment people: effects at the 14-month follow-up / Sale, Alessandro; Noale, Marianna; Cintoli, Simona; Tognoni, Gloria; Braschi, Chiara; Berardi, Nicoletta; Maggi, Stefania; Maffei, Lamberto; Picano, E; Andreassi, Mg; Angelucci, A; Baldacci, F; Baroncelli, L; Begenisic, T; Bellinvia, Pf; Biagi, L; Bonaccorsi, J; Bonanni, E; Bonuccelli, U; Borghini, A; Broccardi, M; Bruno, Rm; Caleo, M; Carlesi, C; Carnicelli, L; Cartoni, G; Cecchetti, L; Cenni, Mc; Ceravolo, R; Chico, L; Cioni, G; Coscia, M; Costa, M; D’Angelo, G; D’Ascanio, P; De Nes, M; Del Turco, S; Di Coscio, E; Di, Galante; M, ; Di, Lascio; N, ; Faita, F; Falorni, I; Faraguna, U; Fenu, A; Fortunato, L; Franco, R; Gargani, L; Gargiulo, R; Ghiadoni, L; Giorgi, Fs; Iannarella, R; Iofrida, C; Kusmic, C; Limongi, F; Maestri, M; Maffei, M; Maggi, S; Mainardi, M; Mammana, L; Marabotti, A; Mariotti, V; Melissari, E; Mercuri, A; Micera, S; Molinaro, S; Narducci, ; R., and Navarra; T, Noale; M, Pagni; C, ; Palumbo, S; Pasquariello, R; Pellegrini, S; Pietrini, P; Pizzorusso, T; Poli, A; Pratali, ; L., and Retico A; Ricciardi, E; Rota, G; Sbrana, S; Scabia, G; Scali, M; Scelfo, D; Sicari, R; Siciliano, G; Stea, F; Taddei, S; Tonacci, A; Tosetti, M; Turchi, S; Volpi, L.. - In: AGE AND AGEING. - ISSN 0002-0729. - 52:5(2023), pp. 1-10. [10.1093/ageing/afad067]
Long-term beneficial impact of the randomised trial ‘Train the Brain’, a motor/cognitive intervention in mild cognitive impairment people: effects at the 14-month follow-up
Cecchetti L;Pietrini P;Ricciardi E;
2023
Abstract
No treatment options are currently available to counteract cognitive deficits and/or delay progression towards dementia in older people with mild cognitive impairment (MCI). The ‘Train the Brain’ programme is a combined motor and cognitive intervention previously shown to markedly improve cognitive functions in MCI individuals compared to non-trained MCI controls, as assessed at the end of the 7-month intervention. Here, we extended the previous analyses to include the long-term effects of the intervention and performed a data disaggregation by gender, education and age of the enrolled participants. We report that the beneficial impact on cognitive functions was preserved at the 14-month follow-up, with greater effects in low-educated compared to high-educated individuals, and in women than in men. © The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved.| File | Dimensione | Formato | |
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